Mouse models of developmental disorders.
The Lillien lab studies developmental disorders of the nervous system.
We have generated a mouse model of preterm birth and are using it to investigate the interaction of this common environmental perturbation and genetic risk factors for developmental disorders.
Representative Publications
Rostral-caudal distribution of Emx1-lineage stem/transit amplifying cells and lineage progression in embryonic cortex depend on Hedgehog signaling.
Lillien L
Developmental Neurobiology (2014)
Akt1 interacts with epidermal growth factor receptors and hedgehog signaling to increase stem/transit amplifying cells in the embryonic mouse cortex.
Sinor-Anderson A, Lillien L
Developmental Neurobiology (2011)